Geneknockout相关论文
目的:探讨肠炎沙门菌n spvD基因对人克隆结肠腺癌Caco-2细胞侵袭力及胞内增殖力的影响。n 方法:利用自杀质粒介导的同源......
由于猪的诸多生理和遗传特征与人类近似,猪一直被认为是理想的异种器官移植候选供体动物.但是物种之间严重的免疫不相容是影响猪到......
Vmhxkl, a pathogenicity-related gene predicted to encode hexokinase, was obtained by amplifying the flanking sequence of......
Objective The hippocampal parallel excitatory pathways referred to as the trisynaptic pathway (entorhinal cortex → dent......
CRISPR/Cas9-mediated gene knockout for DNA methyltransferase Dnmt3a in CHO cells displays enhanced t
DNA methyltransferase Dnmt3a was knocked out by CRISPR/Cas9 technology to construct Dnmt3a-deficient CHO cell expression......
Targeted knock-out of a gene encoding bryoporin in the moss Physcomitrella patens affects leafyshoot
Physcomitrella patens is an extremely dehydration-tolerant moss.Using quantitative two-dimensional difference in-gel ele......
Objective Phosphodiseterase (PDE) is a superfamily of enzymes that catalyzes the hydrolysis of intracellular cAMP and/or......
Analysis of Electrophysiological Remodeling and its Molecular Mechanisms in Mice with Protein X Card
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Gene knockout or inhibition of macrophage migration inhibitory factor alleviates lipopolysaccharide-
Background: Liver injury is one of the most common complications during sepsis. Macrophage migration inhibitory factor (......
Background: Gene knockout has been used to improve the conversion ratio of strains for some chemical products.Based ......
Objective: To discover the roles of Wnt5a and its related genes in the orofacial and palatal development.Methods: Wn......
Anopheles mosquitoes have well-differentiated heteromorphic Y chromosomes.On the other hand, Aedes mosquitoes have h......
ObjectiveTo develop mouse colitis model by inactivating ACE2 gene via TALEN technology.Methods A pair of TALENs targ......
目的 构建并鉴定弓形虫RH株rop16Ⅰ/Ⅲ缺陷虫株.方法 利用CRISPR-Cas9技术进行构建基因缺陷虫株.运用E-CRISPR数据库设计gRNA,并使......
密封蛋白（ Claudin）是细胞间紧密连接的骨架蛋白，参与维持紧密连接的各种功能，其异常表达可破坏上皮细胞及内皮细胞的结构，导致其功能严......
骨组织形成是一个由多种生长因子调节的复杂而有序的过程。骨组织的形成是生物大分子在细胞与细胞之间、细胞与细胞外基质之间的信......
目的 研究p38丝裂原活化蛋白激酶(MAPK)基因敲除对小鼠胚胎成纤维细胞增殖的影响.方法 用蛋白质免疫印迹法(Western blotting)检测......
目的 探讨α1,3半乳糖转移酶(GGTA1)基因敲除巴马克隆猪与核供体巴马猪心、肺解剖学与组织学发育变化的异同.方法 选取GGTA1基因敲......
为探究吕家坨井田地质构造格局,根据钻孔勘探资料,采用分形理论和趋势面分析方法,研究了井田7......
目的 观察腺苷A2A受体基因敲除对小鼠空间学习记忆过程的影响,探讨腺苷A2A受体与空间学习记忆的关系及可能的调节机制.方法 选用腺......
目的 观察白介素6基因敲除(interleukin 6 knockout,IL-6 KO)小鼠原位肝移植后存活时间和肝脏再生的情况. 方法建立正常小鼠(C57BL......
